Redox reactions present one of the most common types of reaction in the living cell and the inanimate world. The ability to monitor these reactions with high sensitivity is scientifically and commercially of tremendous importance. Increasing the sensitivity by one to three orders of magnitude will enable the detection of trace amounts of pollutants and the detection of diseases at an early stage. It will have an impact on environmental issues and medicare. The project combines the success of the amperometric methods (as exploited in the well-known glucose sensor) with the extreme sensitivity of optical detection. The principle of this new method has been established and its development requires the effort of a Europe-wide consortium with expertise in the fields of biotechnology, nanofabrication, materials science, nanoelectronics, biochemistry and biophysics. The project aims to develop this method into a platform technology that allows the application of a range of enzymes in biosensors for the detection of analytes. The sensitivity to be reached will exceed that of currently available sensors.
EdRox: Project description
Seven academic groups with established track records in education and complementary expertise in research participate in this intersectorial and interdisciplinary network together with two SMEs which are active in biotechnology.